METHODS FOR MODULATING EXPRESSION OF C9ORF72 ANTISENSE TRANSCRIPT
摘要
Disclosed herein are methods for reducing expression of C90RF72 antisense transcript in an animal with C90RF72 antisense transcript specific inhibitors. Such methods are useful to treat, prevent, or ameliorate neurodegenerative diseases in an individual in need thereof. Such C90RF72 antisense transcript specific inhibitors include antisense compounds.
申请公布号
CA2926341(A1)
申请公布日期
2015.04.23
申请号
CA20142926341
申请日期
2014.10.14
申请人
IONIS PHARMACEUTICALS, INC.;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;LUDWIG INSTITUTE FOR CANCER RESEARCH
发明人
BENNETT, C. FRANK;RIGO, FRANK;CLEVELAND, DON W.;LAGIER-TOURENNE, CLOTILDE;RAVITS, JOHN M.;BAUGHN, MICHAEL W.
