发明名称 BUFFER FORMULATIONS FOR ENHANCED ANTIBODY STABILITY
摘要 The invention provides buffered formulations of adalimumab. The formulations comprise a buffer comprising an acetate salt, mannitol, glacial acetic acid, sodium chloride, and polysorbate 80. The formulations have an acidic pH, and enhance the thermal, conformational and colloidal stability of antibodies, including the adalimumab antibody.
申请公布号 WO2015057910(A1) 申请公布日期 2015.04.23
申请号 WO2014US60810 申请日期 2014.10.16
申请人 ONCOBIOLOGICS, INC. 发明人 CINI, JOHN;NAGI, ATHENA;TADDEI, MARIA
分类号 A61K39/395 主分类号 A61K39/395
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