发明名称 METHODS FOR USING AUTOLOGOUS FIBROBLASTS TO ALTER SKIN IDENTITY
摘要 The present invention relates to the field of autologous fibroblasts. More specifically, the present invention provides methods and compositions comprising autologous fibroblasts and uses thereof to alter skin identity. In certain embodiments, volar fibroblasts can be expanded for the ability to induce volar skin at the stump site in amputees. In other embodiments, fibroblasts from haired scalp can be expanded to ameliorate alopecias.
申请公布号 US2015110750(A1) 申请公布日期 2015.04.23
申请号 US201314397877 申请日期 2013.04.30
申请人 THE JOHNS HOPKINS UNIVERSITY ;The Government of the United States of America, as represented by the Secretary of the Army 发明人 Garza Luis Andres;Kang Sewon;Meyerle Jon H.
分类号 A61K35/12;C12N5/071 主分类号 A61K35/12
代理机构 代理人
主权项 1. A method for altering skin identity in a patient comprising the step of transplanting autologous fibroblasts into the target skin site of a patient, wherein the autologous fibroblasts are obtained via a skin biopsy from the desired skin type site.
地址 Baltimore MD US