发明名称 METHODS AND KITS FOR DETERMINING A PLACEBO PROFILE IN SUBJECTS FOR CLINICAL TRIALS AND FOR TREATMENT OF PATIENTS
摘要 The present invention is directed to methods and assays for identifying subjects participating in clinical trials that may exhibit a placebo response and identifying treatments for subjects with varying degrees of placebo responses. In one aspect, a method of selecting subjects to participate in a clinical trial is disclosed. In another aspect, methods for treating a subject and determining a treatment dosage are disclosed. In an exemplary embodiment, a method for determining a response to a treatment of a subject having, suspected of having, or at risk for developing a disorder, such as cardiovascular disorder, irritable bowel syndrome, diabetes, autoimmune disorders, inflammation, neurological disorders, chronic pain, cancer, cancer treatments, allergies, depression, migraines, addiction, obesity, and other disorders, syndromes, or diseases, is disclosed.
申请公布号 US2015110718(A1) 申请公布日期 2015.04.23
申请号 US201414516523 申请日期 2014.10.16
申请人 Biometheus LLC 发明人 Winkler Gunther;Hall Kathryn T.;Kaptchuk Ted J.
分类号 C12Q1/68;A61K31/135;A61K31/70;A61K49/00 主分类号 C12Q1/68
代理机构 代理人
主权项 1. A method of selecting a sub-group of human subjects comprising: a) detecting the presence or absence of a catechol-O-methyltransferase polymorphism in a sup-population of human subjects; and b) selecting a sub-group of human subjects from the sup-population wherein the sub-group comprises the presence of the catechol-O-methyltransferase polymorphism.
地址 Naples FL US