BIO-NANO-CHIP FOR ANTICONVULSANT DRUG SALIVARY ASSAY

摘要

This disclosure describes portable bio-nano-chip (BNC) assays of antiepileptic drugs (AED) using salivary samples. The BNC technology results in a more convenient, less expensive, and less time consuming sampling and analysis.

主权项

1. A disposable drug testing cartridge comprising a generally flat substrate having thereon individual bead sensors arranged in an array, wherein each said bead sensor is a porous polymeric bead having a drug bound thereto to form a drug bead sensor, wherein said drug is selected from three or more of valproic acid, phenobarbital, phenytoin, clonazepam, carbamazepine, ethosuximide, felbamate, tiagabine, levetiracetam, lamotrigine, pregabalin, gabapentin, topomax, zonisamide, perampanel, lacosamide, topiramate, oxcarbazepine, and biological metabolites or derivatives of same.