发明名称 |
SUBSTITUTED PYRIDINES AND PYRIMIDINES FOR THE PRODUCTION OF CARDIOMYOCYTE-LIKE CELLS |
摘要 |
<p>Provided are compounds of formula (I) and/or salts thereof, of the class of substituted pyridines and pyrimidines, useful for inducing cardiomyogenesis, a process for producing cardiomyocyte-like cells from mammalian cells by culturing mammalian cells in the presence of the compound of formula (I), the pharmaceutical use of compounds of formula (I) for producing cardiomyocyte-like cells from omnipotent, pluripotent, or lineage committed mammalian cells, and the use of thus produced cardiomyocyte-like cells for treating disorders associated with impaired function of the heart.</p> |
申请公布号 |
EP2519501(B1) |
申请公布日期 |
2015.04.22 |
申请号 |
EP20100803206 |
申请日期 |
2010.12.28 |
申请人 |
TECHNISCHE UNIVERSITÄT WIEN |
发明人 |
MIHOVILOVIC, MARKO;SCHNUERCH, MICHAEL;KOLEY, MOUMITA;HILBER, KARLHEINZ;KOENIG, XAVER |
分类号 |
C07D213/74;A61K31/44;A61K31/505;A61P9/00;C07D239/48;C12N5/00 |
主分类号 |
C07D213/74 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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