| 摘要 |
Disclosed are two endotoxin detection systems and corresponding detection methods thereof. Both of the systems integrate an optical path detection system on the basis of a conventional laser particle size detector and detect the particle size distribution characteristics of the endotoxin colloidal particles in an aqueous solution by using laser light scattering. One of the systems calculates the concentration of the endotoxin by fitting the correlation of the astigmatism with the concentration of the endotoxin according to the differences in scattering intensity of the endotoxin particles at more than three different angles via a quantitative operator. The other system tests the detection parameters of the concentration limits of a series of concentrations of endotoxin standard solutions by the laser light source intensity adjustment, the scanning mode adjustment and the detection parameter adjustment, then selects a corresponding detection parameter to test a sample, and determines whether the sample is satisfactory according to the range of particle size distribution peaks in the detection result. The detection speed is fast, the detection cost is low, and the reliability is high, so the invention can achieve the quantitative detection as well as the single, continuous or online detection of the limits of an endotoxin. |
