| 发明名称 |
IMPROVED PHARMACEUTICAL COMPOSITION CONTAINING DIHYDROPYRIDINE CALCIUM CHANNEL ANTAGONIST AND METHOD FOR THE PREPARATION THEREOF |
| 摘要 |
<p>The present invention relates to the formulation of solid dosage forms comprising a therapeutically effective amount of a dihydropyridine calcium channel antagonist such as Lercanidipine or salt thereof, in combination with colloidal silicon dioxide such as AerosilTM to enhance bioavailability and improve solubility, and a process for the preparation thereof by wet granulation.</p> |
| 申请公布号 |
EP2170295(B1) |
申请公布日期 |
2015.04.22 |
| 申请号 |
EP20080775312 |
申请日期 |
2008.07.23 |
| 申请人 |
PHARMATHEN S.A.;RECORDATI IRELAND LIMITED |
发明人 |
KARAVAS, EVANGELOS;KOUTRIS, MAKIS;SAMARA, VICKY;MATSINGOU, CHRISTINA;ILIOPOULOU, ATHINA |
| 分类号 |
A61K9/20;A61K31/4422 |
主分类号 |
A61K9/20 |
| 代理机构 |
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