发明名称 |
Pharmaceutical formulations of potassium ATP channel openers and uses thereof |
摘要 |
<p>Provided are immediate or prolonged administration of certain potassium ATP (K ATP ) channel openers to a subject to achieve novel pharmacodynamic, pharmacokinetic, therapeutic, physiological, metabolic and compositional outcomes in the treatment of diseases or conditions involving K ATP channels. Also provided are pharmaceutical formulations, methods of administration and dosing of K ATP channel openers that achieve these outcomes and reduce the incidence of adverse effects in treated individuals. Further provided are method of coadministering K AT P channel openers with other drugs to treat diseases of humans and animals.</p> |
申请公布号 |
EP2404605(B1) |
申请公布日期 |
2015.04.22 |
申请号 |
EP20110184285 |
申请日期 |
2005.08.25 |
申请人 |
ESSENTIALIS, INC. |
发明人 |
COWEN, NEIL M.;KASHKIN, KENNETH B. |
分类号 |
A61K31/549;A61K9/22;A61K9/24;A61K9/26;A61K9/28;A61K9/32;A61K9/36;A61K9/52;A61K9/58;A61K9/62 |
主分类号 |
A61K31/549 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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