发明名称 |
COMPOSITIONS AND METHODS FOR SENSITIVE MUTATION DETECTION IN NUCLEIC ACID MOLECULES |
摘要 |
The present disclosure provides methods for detecting mutations in a target nucleic acid molecule by rolling circle amplification of a library of double-stranded circular bar-coded template molecules. Also provided herein are methods for enriching a target nucleic acid molecule. |
申请公布号 |
EP2861769(A1) |
申请公布日期 |
2015.04.22 |
申请号 |
EP20130805132 |
申请日期 |
2013.06.14 |
申请人 |
FRED HUTCHINSON CANCER RESEARCH CENTER |
发明人 |
BIELAS, JASON, H.;ERICSON, NOLAN, G. |
分类号 |
C12Q1/68;C12N15/11;G01N33/53 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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