| 主权项 |
1. A process for the preparation of 2-methoxymethyl-1,4-benzenediamine, other compounds of formula (IV) and the salts thereof comprising:
a) performing a reduction of a compound of formula (I) to prepare a compound of formula (II) b) performing an etherification of the compound of formula (II) to prepare a compound of formula (III) c) performing a hydrogenation of the compound of formula (III) to prepare a compound of formula (IV); wherein R1, R2, and R3 are substituents selected from the group consisting of:
i) C-linked substituents selected from the group consisting of:
a) alkyl groups;b) aryl groups; andc) substituents selected from the group consisting of COOA1, CONA1, CONA1COA2, C(═NA1)NA1A2, and CN;
wherein the C-linked substituents comprise from 1 to about 10 carbon atoms and from 0 to about 5 heteroatoms selected from the group consisting of O, F, Cl, N, P, Si, and combinations thereof;ii) S-linked substituents selected from the group consisting of SA1, SO2A1, SO3A1, SSA1, SOA1, SO2NA1A2, SNA1A2, and SONA1A2;iii) O-linked substituents selected from the group consisting of OA1, ONA1A2;iv) N-linked substituents selected from the group consisting of NA1A2; (NA1A2A3)+, NA1SA2, NO2;v) halogens selected from the group consisting of F, Cl, Br, and I;vi)hydrogen; andvii) combinations thereof;wherein A1, A2, and A3 are alkyl groups comprising from 1 to about 10 carbon atoms and from 0 to about 5 heteroatoms selected from the group consisting of O, F, Cl, N, P, Si, and combinations thereof; wherein R5 is an alkyl group; and wherein R6 and R7 are selected from the group consisting of hydrogen, hydroxyl groups, alkyl groups, aminoalkyl groups, hydroxyalkyl groups, and combinations thereof. |
