Volume-labeled nanoparticles and methods of preparation

摘要

Compositions comprising nanosized objects (i.e., nanoparticles) in which at least one observable marker, such as a radioisotope or fluorophore, is incorporated within the nanosized object. The nanosized objects include, for example, metal or semi-metal oxide (e.g., silica), quantum dot, noble metal, magnetic metal oxide, organic polymer, metal salt, and core-shell nanoparticles, wherein the label is incorporated within the nanoparticle or selectively in a metal oxide shell of a core-shell nanoparticle. Methods of preparing the volume-labeled nanoparticles are also described.

主权项

1. A method for synthesizing volume-labeled nanosized objects, the method comprising reacting nanoparticle precursor molecules in the presence of at least one observable marker to produce said volume-labeled nanosized objects.