发明名称 |
Implantable medical device including a protection/retaining layer for an active ingredient or drug, in particular a water-soluble one |
摘要 |
An implantable medical device (10) comprises reservoirs (30) for receiving a water-soluble active agent or medicament (36) in the form of a solid deposit; and at least one biocompatible and biodegradable protecting/retaining layer (38) for protecting the active agent or medicament (36) until it reaches its site of implantation, said biocompatible and biodegradable protecting layer (38) comprising at least one biocompatible and biodegradable film-forming agent, and at least one hydrophobic, biocompatible, agent for controlling the disintegration rate of the protecting/retaining layer. The invention provides better protection of the active agent or medicament and better control of the disintegration rate of the protecting/retaining layer. |
申请公布号 |
US9011519(B2) |
申请公布日期 |
2015.04.21 |
申请号 |
US200912918644 |
申请日期 |
2009.02.20 |
申请人 |
Hexacath |
发明人 |
Ascher Gilles;Camenzind Edoardo |
分类号 |
A61F2/06;A61L31/10;A61L31/16 |
主分类号 |
A61F2/06 |
代理机构 |
Lucas & Mercanti, LLP |
代理人 |
Lucas & Mercanti, LLP |
主权项 |
1. An implantable medical device to be implanted at a site of implantation, comprising at least one therapeutically active agent or medicament, comprising:
receiving means for receiving at least a layer consisting essentially of said active agent or medicament, in the form of a solid deposit; and at least one biocompatible and biodegradable protecting/retaining layer for protecting the active agent or medicament until it is at its site of implantation, said biocompatible and biodegradable protecting/retaining layer comprising at least one biocompatible and biodegradable film-forming agent and at least one hydrophobic, biocompatible, agent in an amount sufficient to control the disintegration rate of the protecting/retaining layer. |
地址 |
Bellizona CH |