Heart valve assembly systems and methods

摘要

Heart valve assembly systems and methods configured for medical interventional procedures. In one aspect, the methods and systems involve a modular approach to treatment.

主权项

1. A mitral heart valve assembly system configured for staged implantation at a native mitral valve site via an endovascular access to a heart, comprising:
an anchor to implant along a native mitral valve annulus while the native mitral valve remains functional, the anchor including: a supra-annular structure configured to reside above the valve annulus of the native mitral valve and defining a first geometric interlock face at an uppermost portion of the anchor; and a plurality of commissural projections that extend downwardly away from the supra-annular structure and that are sized and shaped to extend between the native mitral valve leaflets without interfering with the functionality of native mitral valve leaflets, wherein the commissural projections are configured to anchor along native heart tissue below the valve annulus of the native mitral valve without interfering with the functionality of native mitral valve leaflets; and a valve assembly configured to subsequently implant after the anchor in the staged implantation via the endovascular access to the heart, wherein the valve assembly includes: an occluder component having a plurality of leaflets formed from pericardial tissue and positioned to occlude blood flow during systole and open to blood flow during diastole; a support component to maintain a portion of the occluder component in a supra-annular position above the valve annulus of the native mitral valve and further having a second geometric interlock face sized and shaped to lockingly and directly engage the first geometric interlock face of the supra-annular structure of the anchor; and a lower contoured portion configured to engage with the native mitral valve, wherein at least a portion of the lower contoured portion is tapered inwardly and configured to extend below the valve annulus of the native mitral valve.