发明名称 Biocompatible and biodegradable elastomeric polymers
摘要 Disclosed herein are biocompatible and biodegradable polymers which are useful in tissue engineering, wound healing, coatings, and drug delivery, the polymers comprising one or more ECM-mimetic peptides and one or more biodegradable moieties, wherein the moieties do not comprise an amino acid or residue thereof. Further disclosed herein are methods for making and using the disclosed biocompatible polymers.
申请公布号 US9011918(B2) 申请公布日期 2015.04.21
申请号 US201213566392 申请日期 2012.08.03
申请人 Evonik Corporation 发明人 Pattanaik Asima
分类号 A61K38/08;A61K47/42;C07K7/06;A61K47/48;A61L27/18;A61L27/22;A61L27/58;A61L31/10;A61K9/00;A61K9/16;A61K47/34 主分类号 A61K38/08
代理机构 代理人 Li Linda S.;Ngui Jason S.
主权项 1. A biocompatible polymer comprising: a) one or more ECM-mimetic peptides having the amino acid sequence GVGVP as set forth in SEQ ID NO: 29; and b) one or more biodegradable moieties, wherein the moieties do not comprise an amino acid or residue thereof; wherein the polymer has a weight-average molecular weight of from about 1,000 Da to about 2,000,000 Da.
地址 Parsippany NJ US