Anti-DLL3 antibody drug conjugates and methods of use

摘要

Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.

主权项

1. A method of reducing the frequency of tumor initiating cells in a subject comprising administering to the subject an anti-DLL3 antibody drug conjugate (ADC), or a pharmaceutically acceptable salt thereof, in an amount effective for the reduction of tumor initiating cells in the subject.