发明名称 Ethyl (2R)-2-acetamido-3-(4-methylbenzoylsulfanyl)propanoate and uses thereof
摘要 A novel substituted N-acetyl-L-cysteine (NAC) derivative and methods of using this compound for the treatment of diseases and/or conditions, including but not limited to diseases and/or conditions of, or involving, the Central Nervous System (CNS), including schizophrenia adrenoleukodystrophy, mitochondrial diseases (e.g. Leigh syndrome, Alpers' disease, and MELAS), Huntington's disease, trichotillomania, HIV-associated neurocognitive disorder, hypoxic-ischemic encephalopathy, drug craving, and drug addiction.
申请公布号 US9012674(B1) 申请公布日期 2015.04.21
申请号 US201414535953 申请日期 2014.11.07
申请人 Promentis Pharmaceuticals, Inc. 发明人 Neary Michael;Nieman James;Tanis Steven;Lawton Daniel
分类号 C07C327/34;A61K31/265;C07C327/00 主分类号 C07C327/34
代理机构 Wood, Phillips, Katz, Clark & Mortimer 代理人 Wood, Phillips, Katz, Clark & Mortimer
主权项 1. A compound of formula I,or a pharmaceutically acceptable salt or ester thereof.
地址 Milwaukee WI US