发明名称 |
Ethyl (2R)-2-acetamido-3-(4-methylbenzoylsulfanyl)propanoate and uses thereof |
摘要 |
A novel substituted N-acetyl-L-cysteine (NAC) derivative and methods of using this compound for the treatment of diseases and/or conditions, including but not limited to diseases and/or conditions of, or involving, the Central Nervous System (CNS), including schizophrenia adrenoleukodystrophy, mitochondrial diseases (e.g. Leigh syndrome, Alpers' disease, and MELAS), Huntington's disease, trichotillomania, HIV-associated neurocognitive disorder, hypoxic-ischemic encephalopathy, drug craving, and drug addiction. |
申请公布号 |
US9012674(B1) |
申请公布日期 |
2015.04.21 |
申请号 |
US201414535953 |
申请日期 |
2014.11.07 |
申请人 |
Promentis Pharmaceuticals, Inc. |
发明人 |
Neary Michael;Nieman James;Tanis Steven;Lawton Daniel |
分类号 |
C07C327/34;A61K31/265;C07C327/00 |
主分类号 |
C07C327/34 |
代理机构 |
Wood, Phillips, Katz, Clark & Mortimer |
代理人 |
Wood, Phillips, Katz, Clark & Mortimer |
主权项 |
1. A compound of formula I,or a pharmaceutically acceptable salt or ester thereof. |
地址 |
Milwaukee WI US |