| 发明名称 |
QUINOLINE DERIVATIVES AS PI3 KINASE INHIBITORS |
| 摘要 |
<p>Invented is a method of inhibiting the activity/function of PB kinases using quinoline derivatives of Formula I. Also invented is a method of treating one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, allergy, asthma, pancreatitis, multiorgan failure, kidney diseases, platelet aggregation, cancer, sperm motility, transplantation rejection, graft rejection and lung injuries by the administration of quinoline derivatives. (see formula I)</p> |
| 申请公布号 |
CA2686016(C) |
申请公布日期 |
2015.04.21 |
| 申请号 |
CA20082686016 |
申请日期 |
2008.05.16 |
| 申请人 |
SMITHKLINE BEECHAM CORPORATION |
发明人 |
ADAMS, NICHOLAS D.;BURGESS, JOELLE LORRAINE;DARCY, MICHAEL GERARD;DONATELLI, CARLA A.;KNIGHT, STEVEN DAVID;NEWLANDER, KENNETH ALLEN;RIDGERS, LANCE;SARPONG, MARTHA;SCHMIDT, STANLEY J. |
| 分类号 |
C07D401/14;A61K31/4709;A61K31/495;A61K31/5377;A61P35/00;C07D401/10;C07D405/14;C07D413/14;C07D471/04;C07D493/04;C07D498/04 |
主分类号 |
C07D401/14 |
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