发明名称 |
FREMGANGSMÅDE TIL MODULERING AF EKSPRESSION AF EPIDERMAL VÆKSTFAKTORRECEPTOR (EGFR), DER INDEBÆRER MIRNA |
摘要 |
<p>The present invention relates to a method for modulating the expression of epidermal growth factor receptor (EGFR) and its downstream signalling effectors. In particular, the present invention relates to a method for modulating the expression of epidermal growth factor receptor (EGFR) or like molecule in a cell comprising contacting said cell with an agent capable of directly or indirectly interacting with the 3'-untranslated region (UTR) of the mRNA of said EGFR or like molecule, wherein the UTR is encoded by a sequence which comprises a sequence having at least about 70% identity with at least one sequence selected from the group consisting of the sequences set forth in SEQ ID NOs: 1-36.</p> |
申请公布号 |
DK2061482(T3) |
申请公布日期 |
2015.04.20 |
申请号 |
DK20070800215T |
申请日期 |
2007.08.28 |
申请人 |
THE UNIVERSITY OF WESTERN AUSTRALIA |
发明人 |
LEEDMAN, PETER;GILES, KEITH;WEBSTER, REBECCA, JANE |
分类号 |
A61K31/7105;A61K31/711;A61K48/00;A61P35/00;C12N15/113 |
主分类号 |
A61K31/7105 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|