发明名称 MULTIPLEX HER2 AND ESTROGEN RECEPTOR CO-STAINING ASSAYS FOR DETECTING TUMOR HETEROGENEITY
摘要 Disclosed herein are methods for detecting the presence and/or amount of HER2 protein, HER2 nucleic acid (for example, HER2 genomic DNA), ER protein, and Chromosome 17 centromere DNA in a single sample. Samples stained for HER2 protein, HER2 DNA, ER protein, and Chromosome 17 DNA allow for the identification of various types of cancer cells, for example HER2 protein positive/ER protein positive/HER2 gene positive cells, HER2 protein positive/ER protein negative/HER2 gene positive cells, HER2 protein negative/ER protein positive/HER2 gene positive cells, and HER2 protein negative/ER protein negative/HER2 gene positive cells.
申请公布号 CA2942081(A1) 申请公布日期 2015.04.16
申请号 CA20142942081 申请日期 2014.10.09
申请人 VENTANA MEDICAL SYSTEMS, INC.;NIHON UNIVERSITY SCHOOL OF MEDICINE 发明人 NITTA, HIRO;KELLY, BRIAN D.;DENNIS, ESLIE;MASUDA, SHINOBU
分类号 C12Q1/68;G01N33/50;G01N33/58 主分类号 C12Q1/68
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