BIOMARKERS FOR LOWER URINARY TRACT SYMPTOMS (LUTS)

摘要

Provided herein are compositions and methods for the characterization of a subject's predisposition to developing lower urinary tract symptoms (LUTS). In particular, biomarkers are provided that identify the likelihood that a subject with develop LUTS concomitant with pelvic organ prolapse (POP), and/or the likelihood that LUTS will persist after surgical repair of POPS.

主权项

1. A method for assessing the likelihood a human female subject will develop LUTS comprising detecting the level of one or more biomarkers in a sample, wherein the level of the one or more biomarkers is indicative of likelihood of developing LUTS, and wherein the biomarkers are one or more biomarkers selected from the list consisting of: hbegf, IL-6, ngf, IL-10, Gro, SCD40L, MCP-1, IL-3, IP-10, IL-12, MCP 3, and MIP-1b.