ORGAN STORAGE SOLUTION

摘要

The invention relates to a storage solution for the preservation of organs, tissue or organ systems to be transplanted, said solution being based on the known HTK, UW or Celsior solutions. In accordance with the invention it has been determined that ischemia and reperfusion injury could be reduced through the addition of ectoine or hydroxyectoine.

主权项

1. Storage solution for the preservation of organs, tissue or organ systems to be transplanted, said storage solution containing
histidine, tryptophan, and α-ketoglutarate or corresponding salts or lactobionic acid and/or raffinose as well as hydroxyethyl starch or corresponding salts or mannitol, lactobionic acid, glutamic acid, histidine, calcium chloride, potassium chloride, magnesium chloride, sodium hydroxide, and glutathione or corresponding salts, characterized in that, the storage solution contains ectoine, hydroxyectoine and/or a salt, ester, or amide of ectoine or hydroxyectoine.