发明名称 Inhibitors of influenza viruses replication
摘要 Methods of inhibiting the replication of influenza viruses in a biological sample or patient, of reducing the amount of influenza viruses in a biological sample or patient, and of treating influenza in a patient, comprises administering to said biological sample or patient an effective amount of a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula (IA) are as described herein. A compound is represented by Structural Formula (IA) or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula (IA) are as described herein. A pharmaceutical composition comprises an effective amount of such a compound or pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, adjuvant or vehicle.
申请公布号 AU2010262905(B2) 申请公布日期 2015.04.16
申请号 AU20100262905 申请日期 2010.06.17
申请人 VERTEX PHARMACEUTICALS INCORPORATED 发明人 CHARIFSON, PAUL;CLARK, MICHAEL P.;BANDARAGE, UPUL K.;BETHIEL, RANDY S.;COURT, JOHN J.;DENG, HONGBO;DRUTU, IOANA;DUFFY, JOHN P.;FARMER, LUC;GAO, HUAI;GU, WENXIN;JACOBS, DYLAN H.;KENNEDY, JOSEPH M.;LEDEBOER, MARK W.;LEDFORD, BRIAN;MALTAIS, FRANCOIS;PEROLA, EMANUELE;WANG, TIANSHENG;WANNAMAKER, M WOODS;BYRN, RANDAL;ZHOU, YI;LIN, CHAO;JIANG, MIN;JONES, STEVEN;GERMANN, URSULA A.;SALITURO, FRANCESCO G.;KWONG, ANN DAK-YEE
分类号 A61K31/506;A61P31/16 主分类号 A61K31/506
代理机构 代理人
主权项
地址