发明名称 |
PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING |
摘要 |
The invention provides novel inhibitors of hedgehog signaling that are useful as a therapeutic agents for treating malignancies where the compounds have the general formula I:;;wherein A, X, Y R1, R2, R3, R4, m and n are as described herein. |
申请公布号 |
US2015105550(A1) |
申请公布日期 |
2015.04.16 |
申请号 |
US201414575018 |
申请日期 |
2014.12.18 |
申请人 |
GENENTECH, INC. ;CURIS, INC. |
发明人 |
GUNZNER Janet L.;SUTHERLIN Daniel;STANLEY Mark S.;BAO Liang;CASTANEDO Georgette M.;LALONDE Rebecca L.;WANG Shumei;REYNOLDS Mark E.;SAVAGE Scott J.;MALESKY Kimberly;DINA Michael S.;KOEHLER Michael F.T. |
分类号 |
C07D417/12;C07D413/12;C07D213/56;C07D409/12;C07D401/12;C07D401/14 |
主分类号 |
C07D417/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
South San Francisco CA US |