COMPLIANT CRYOBALLOON APPARATUS FOR DENERVATION OSTIA OF THE RENAL ARTERIES

摘要

A cryotherapy balloon catheter includes a compliant cryotherapy balloon comprising a distal balloon section dimensioned for placement within a renal artery and a proximal balloon section dimensioned to abut against an ostium of the renal artery and extend into at least a portion of the abdominal aorta. The compliant balloon has a diameter that varies non-uniformly along a length of the compliant balloon, such that a diameter at the proximal balloon section is larger than a diameter of the distal balloon section. The cryotherapy balloon catheter may be configured to deliver cryogenic therapy to at least the ostium of the renal artery sufficient to irreversibly terminate renal sympathetic nerve activity, such as by causing neurotmesis of renal nerve fibers and ganglia at the ostium of the renal artery.

主权项

1. An ablation balloon catheter apparatus, comprising:
a flexible shaft comprising a proximal end, a distal end, and a lumen arrangement extending between the proximal and distal ends, the shaft having a length sufficient to access a patient's renal artery relative to a percutaneous access location; a balloon provided at the distal end of the shaft and fluidly coupled to the lumen arrangement, the balloon having a longitudinal axis extending from a proximal end to a distal end thereof; and an ablation member extending helically around the balloon in an axial direction.