DEVICES AND CARTRIDGES FOR EXTRACTING BIO-SAMPLE REGIONS AND MOLECULES OF INTEREST

摘要

Methods, devices, and systems for integrating extraction and purification of bio-sample regions and materials with patient analysis, diagnosis, follow up, and treatment. The invention provides a means to insert disclosed substrates, cartridges, and cartridge-processing instrument or instruments into a standard clinic or pathology laboratory workflow. Specifically, we disclose methods, devices, and systems for inserting standard pathology slides into disclosed cartridges and cartridge-processing instruments, either manually, semi-automatically, automatically, or by robotic means.

主权项

1. A cartridge for extracting biological material from a biological sample, the cartridge comprising:
a film pre-loaded on the cartridge, wherein the film comprises a substrate suitable for extracting biological material from the biological sample; an adjustable link for attaching the cartridge to a slide upon which the biological sample has been mounted, wherein the cartridge and slide form a single unit after attaching the cartridge to the slide; a mechanism for pressing the film against the biological sample mounted on the slide when the slide is attached to the cartridge; a mechanism for ending the pressing of the film against the biological sample mounted on the slide when the slide is attached to the cartridge; a pull tab which is attached to the film, wherein the pull tab enables the film to be removed from the cartridge.