发明名称 |
HYDROPHILIC NANOPARTICLES SURFACE-MODIFIED WITH MONOSACCHARIDE PHOSPHATE OR MONOSACCHARIDE PHOSPHATE DERIVATIVES, ITS COLLOIDAL SOLUTION AND USE THEREOF |
摘要 |
Disclosed are a composition including hydrophilic nanoparticles that have a monosaccharide-phosphate or a derivative thereof adhered to the surface thereof, a colloidal solution of the composition dispersed in water, and a magnetic resonance imaging contrast agent including the colloidal solution. According to the present invention, nanoparticles having biocompatibility and excellent water-dispersibility can be prepared by modifying the surface of inorganic nanoparticles. The prepared nanoparticles may be effectively used in a variety of applications including, for example, in vivo imaging applications such as an MRI contrast agent, nano-electronic convergence technologies such as a quantum dot light emitting device, biomedical applications such as hyperthermia, or the like. Moreover, compared to existing nanoparticles dispersed by a dispersion stabilizer known in the art, excellent dispersion stability and a relatively small hydrodynamic diameter may be attained. |
申请公布号 |
EP2739271(A4) |
申请公布日期 |
2015.04.15 |
申请号 |
EP20120819297 |
申请日期 |
2012.08.03 |
申请人 |
HANWHA CHEMICAL CORPORATION |
发明人 |
KIM, EUNG GYU;JEON, BONG-SIK;KWON, EUN BYUL;PARK, JU YOUNG;MYEONG, WAN JAE |
分类号 |
A61K9/16;A61K47/30;A61K47/48 |
主分类号 |
A61K9/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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