<p>An oral care composition having a first phase of clinically efficacious 2,4,4′-trichloro 2′-hydroxydiphenyl ether admixed in a first orally acceptable aqueous vehicle, and a second phase having a stannous salt (such as stannous fluoride) admixed in a second orally acceptable aqueous vehicle. The second phase has no less than 10 molar percent of soluble stannous ion respective to a mathematical sum of moles of the soluble stannous ion and moles of the stannous salt in the second phase. In one embodiment, the two phases are provided in a dual-tube toothpaste oral care kit.</p>
申请公布号
EP1830821(B1)
申请公布日期
2015.04.15
申请号
EP20050824822
申请日期
2005.11.18
申请人
COLGATE-PALMOLIVE COMPANY
发明人
FRUGE, LINH;BROWN, JAMES, R.;HERLES, SUSAN;PANALIGAN, KIMBERLEE;ARVANITIDOU, EVANGELIA, S.;MILANOVICH, NEBOJSA;PRENCIPE, MICHAEL