| 发明名称 |
ANGIOPOIETIN-LIKE 3 (ANGPTL3) IRNA COMPOSTIONS AND METHODS OF USE THEREOF |
| 摘要 |
The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the ANGPTL3 gene, as well as methods of inhibiting expression of ANGPTL3 and methods of treating subjects having a disorder of lipid metabolism, such as hyperlipidemia or hypertriglyceridemia, using such dsRNA compositions. |
| 申请公布号 |
EP2723758(A4) |
申请公布日期 |
2015.04.15 |
| 申请号 |
EP20120802093 |
申请日期 |
2012.06.20 |
| 申请人 |
ALNYLAM PHARMACEUTICALS |
发明人 |
BETTENCOURT, BRIAN;QUERBES, WILLIAM;FITZGERALD, KEVIN;FRANK-KAMENETSKY, MARIA;MILSTEIN, STUART;SHULGA-MORSKAYA, SVETLANA |
| 分类号 |
C07H21/04 |
主分类号 |
C07H21/04 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
