发明名称 Anticorpos modificadores de doença cancerígena.
摘要 <p>The present invention relates to a method for producing cancerous disease modifying antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer cell cytotoxicity as an end point, the process makes possible the production of anti-cancer antibodies for therapeutic and diagnostic purposes. The antibodies can be used in aid of staging and diagnosis of a cancer, and can be used to treat primary tumors and tumor metastases. The anti-cancer antibodies can be conjugated to toxins, enzymes, radioactive compounds, and hematogenous cells.</p>
申请公布号 BRPI0816181(A2) 申请公布日期 2015.04.14
申请号 BR2008PI16181 申请日期 2008.08.26
申请人 F.HOFFMANN-LA ROCHE AG 发明人 DAVID S. F. YOUNG;HELEN P. FINDLAY;SUSAN E. HAHN;LISA M. CECHETTO
分类号 C07K16/30;A61K39/395;A61K47/48;A61K51/10;A61P35/00;A61P37/04;C07K14/705;C07K16/46;C07K19/00;C12N5/16;C12P21/08;G01N33/574;G01N33/577 主分类号 C07K16/30
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