发明名称 |
Therapeutic or prophylactic agent for cachexia |
摘要 |
A therapeutic or prophylactic agent for cachexia includes as an effective ingredient a compound having a specified morphinan skeleton represented by a compound of the following structure:;
or a pharmacologically acceptable acid addition salt thereof. |
申请公布号 |
US9006262(B2) |
申请公布日期 |
2015.04.14 |
申请号 |
US201213982578 |
申请日期 |
2012.01.30 |
申请人 |
Toray Industries, Inc. |
发明人 |
Suzuki Tomohiko;Yoshizawa Yoshitaka;Hirakata Mikito |
分类号 |
A61K31/44;A61K31/485 |
主分类号 |
A61K31/44 |
代理机构 |
DLA Piper LLP (US) |
代理人 |
DLA Piper LLP (US) |
主权项 |
1. A method of treating cachexia comprising administering a therapeutically effective amount of a compound of Formula (I): to a patient, wherein a double line consisting of a broken line and a solid line represents a double bond or single bond, R1 represents C4-C7 cycloalkylalkyl, R2 represents C1-C5 linear or branches alkyl, and B represents —CH═CH— or a pharmacologically acceptable acid addition salt thereof. |
地址 |
JP |