Plasmonic assisted systems and methods for interior energy-activation from an exterior source

摘要

A method and a system for producing a change in a medium disposed in an artificial container. The method places in a vicinity of the medium at least one of a plasmonics agent and an energy modulation agent. The method applies an initiation energy through the artificial container to the medium. The initiation energy interacts with the plasmonics agent or the energy modulation agent to directly or indirectly produce the change in the medium. The system includes an initiation energy source configured to apply an initiation energy to the medium to activate the plasmonics agent or the energy modulation agent.

主权项

1. A method for producing a change in a medium, comprising:
(1) placing inside the medium to be treated an energy modulation agent and a photoactivatable agent, said energy modulation agent comprising a photon emitter which emits at least one of ultraviolet and visible light into the medium to be treated upon interaction with an initiation energy; (2) applying the initiation energy from an energy source including at least one of x-rays, gamma rays, or an electron beam to the medium said at least one of ultraviolet and visible light one or more positions displaced from the energy modulation agent inside the medium to be treated; and (3) inducing, from the light emitted into the medium to be treated, a photoreactive change to the photoactivatable agent displaced from the energy modulation agent inside the medium to be treated, wherein inducing a photoreactive change includes activating in vivo a photoreactive drug in the medium to be treated.