发明名称 |
Inhibition of bacterial biofilms with imidazole-phenyl derivatives |
摘要 |
Disclosure is provided for imidazole-phenyl derivative compounds that prevent, remove and/or inhibit the formation of biofilms, compositions comprising these compounds, devices comprising these compounds, and methods of using the same. |
申请公布号 |
US9005643(B2) |
申请公布日期 |
2015.04.14 |
申请号 |
US200912417981 |
申请日期 |
2009.04.03 |
申请人 |
North Carolina State University |
发明人 |
Melander Christian;Richards Justin J.;Bunders Cynthia |
分类号 |
A01N43/50;A01P1/00;A61K31/4168;A61K31/397;C07D233/88;C07D405/12;C07D409/12;C07D403/10 |
主分类号 |
A01N43/50 |
代理机构 |
Myers Bigel Sibley & Sibley & Sajovec, P.A. |
代理人 |
Myers Bigel Sibley & Sibley & Sajovec, P.A. |
主权项 |
1. A composition comprising a compound of Formula (I)(a): wherein:
R1 is C5 or C6 alkyl;R1′, R2 and R2′ are each H; andn=0;or a pharmaceutically acceptable salt thereof and a carbapenem antibiotic. |
地址 |
Raleigh NC US |