发明名称 Inhibition of bacterial biofilms with imidazole-phenyl derivatives
摘要 Disclosure is provided for imidazole-phenyl derivative compounds that prevent, remove and/or inhibit the formation of biofilms, compositions comprising these compounds, devices comprising these compounds, and methods of using the same.
申请公布号 US9005643(B2) 申请公布日期 2015.04.14
申请号 US200912417981 申请日期 2009.04.03
申请人 North Carolina State University 发明人 Melander Christian;Richards Justin J.;Bunders Cynthia
分类号 A01N43/50;A01P1/00;A61K31/4168;A61K31/397;C07D233/88;C07D405/12;C07D409/12;C07D403/10 主分类号 A01N43/50
代理机构 Myers Bigel Sibley & Sibley & Sajovec, P.A. 代理人 Myers Bigel Sibley & Sibley & Sajovec, P.A.
主权项 1. A composition comprising a compound of Formula (I)(a): wherein: R1 is C5 or C6 alkyl;R1′, R2 and R2′ are each H; andn=0;or a pharmaceutically acceptable salt thereof and a carbapenem antibiotic.
地址 Raleigh NC US