发明名称 Thermal apparatus
摘要 Provided herein are an apparatus and methods to induce electromagnetic field in biologic tissue for thermal therapy. The apparatus comprises electromagnetic devices fitted to be releasably deployed inside a body, magnetic materials to be deployed in a body, and a magnetic centrifuge machine. An electromagnetic device includes a controllably flexible fiberoptic tubular device with a magnetic-flux-controlled electromagnetic assembly on its distal end. The electromagnetic device receives direct or alternating electric current. Implanted particulate magnetic materials in close proximity to said electromagnetic assembly form reversible magnetic vascular mold in target blood vessels by static magnetic field produced by direct electric current to said electromagnetic assembly. Implanted magnetic materials generate heat by alternating magnetic field induced by alternating electric current to said electromagnetic assembly. A magnetic centrifuge machine removes magnetic materials from blood by centrifugation under static magnetic field after completion of thermal therapy.
申请公布号 US9005151(B2) 申请公布日期 2015.04.14
申请号 US201113227189 申请日期 2011.09.07
申请人 发明人 Lee Choon Kee
分类号 A61N2/12;A61M1/36;A61N1/40;A61M5/44 主分类号 A61N2/12
代理机构 代理人
主权项 1. A thermal apparatus comprising: a flexible tubular device, having a proximal end, a distal end, a flexible tubular portion connecting said proximal and distal ends, and a fiberoptic system, which is provided as one or a plurality of operating devices having one or a plurality of mechanical configurations, and which is configured for insertion into a lumen or a cavity of a body to reach a target area and which provides electromagnetic field in said target area; the distal end, which is provided as one or a plurality of operating devices having one or a plurality of mechanical configurations and which connects to said flexible tubular portion, and which encloses an electromagnetic assembly that receives electric current to generate electromagnetic field; the flexible tubular portion, provided as one or a plurality of operating devices having one or a plurality of mechanical configurations and which carries electrically conductive wires to said electromagnetic assembly of said distal end, one or a plurality of conduits and cables, and which provides navigation of said device; and the fiberoptic system, which is provided as one or a plurality of operating devices having one or a plurality of mechanical configurations and which is made of one or a plurality of high temperature-and electromagnetic-field-tolerant optical materials, and which provides visual assessment and infrared thermometry of areas of a lumen or a cavity of a body, which receive therapy with electromagnetic field; a transphasic fluid of one or a plurality of solutions, which suspends a plurality of magnetic particles in one or a plurality of concentrations, which is to be administrated to blood vessels through vascular catheter to target blood vessels connected to a target area and which is to be reversibly electromagnetically paired with an electromagnetic assembly of a flexible fiberoptic tubular device of said thermal apparatus inserted into a lumen or a cavity of a body to reach said target area; the transphasic fluid comprises magnetic particles of different sizes and shapes combined together at varying ratios; the transphasic fluid is in liquid phase off static electromagnetic field and in gel-like or semi-solid phase on static electromagnetic field; the gel-like transphasic fluid of magnetic particles introduced to target blood vessels are to get localized in the target blood vessels of the target area and to form internal mold of reversible random lattice structure made of magnetic particles inside said target blood vessels by one or a plurality of static electromagnetic fields generated from direct electric current to said electromagnetic assembly; and the magnetic particles of said gel-like transphasic fluid producing said internal mold of said blood vessels generate heat energy under alternating electromagnetic field, which is to achieve temperature of said target blood vessels and said target area high enough to make tissue of said target blood vessels and said target area die but low enough to avoid damage to normal tissue adjacent to said target blood vessels and said target area over a range of duration.
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