主权项 |
1. A method of determining blood glucose concentration with a glucose measurement system that comprises a test strip and test meter, the test meter having a microcontroller configured to apply a plurality of test voltages to the test strip and measure at least a current transient output resulting from an electrochemical reaction in a test chamber of the test strip, the method comprising:
inserting the test strip into a strip port connector of the test meter to connect at least two electrodes coupled to the test chamber of the test strip to a strip measurement circuit; initiating a test sequence after deposition of a sample, in which the initiating comprises:
applying a first voltage of approximately ground potential to the test chamber for a first duration;applying a second voltage to the test chamber for a second duration after the first duration;changing the second voltage to a third voltage different from the second voltage for a third duration after the second duration;switching the third voltage to a fourth voltage different from the third voltage for a fourth duration after the third duration;altering the fourth voltage to a fifth voltage different from the fourth voltage for a fifth duration after the fourth duration;modifying the fifth voltage to a sixth voltage different from the fifth voltage for a sixth duration after the fifth duration;changing the sixth voltage to a seventh voltage different from the sixth voltage for a seventh duration after the sixth duration, wherein each of the second to seventh voltages comprises about one millivolt; measuring at least one of:
a first current transient output from the test chamber during a first interval proximate the second and third durations;a second current transient output during a second interval proximate the fourth and fifth durations;a third current transient output during a third interval proximate the fifth and sixth durations;a fourth current transient output during a fourth interval proximate the sixth and seventh durations; anda fifth current transient output during a fifth interval proximate the end of the seventh durations; calculating a glucose concentration of the sample from at least one of the first, second, third, fourth, or fifth current outputs such that bias in the glucose concentration is less than ±10% for glucose concentrations less than 75 mg/dL in hematocrits ranging from about 20% to about 60%. |