发明名称 Bone cell delivery device
摘要 Bone cages are disclosed including devices for biocompatible implantation. The structures of bone are useful for providing living cells and tissues as well as biologically active molecules to subjects.
申请公布号 US9005944(B2) 申请公布日期 2015.04.14
申请号 US200711906664 申请日期 2007.10.02
申请人 The Invention Science Fund I, LLC 发明人 Harlow Ed;Jung Edward K. Y.;Langer Robert;Leuthardt Eric C.;Wood, Jr. Lowell L.
分类号 C12N9/00;A61K9/48;A61K47/48;A61K9/00;A61L27/36;A61L27/38;C12N5/077;A61K35/12 主分类号 C12N9/00
代理机构 Dorsey & Whitney LLP 代理人 Dorsey & Whitney LLP
主权项 1. A method of making a device, comprising: culturing bone cells in vitro on a scaffold to form an implantable structure; forming an internal cavity in the implantable structure; and selectively drilling, in the implantable structure, a first plurality of pores at a first location and a second plurality of pores at a second location, wherein the first location is discrete from the second location, wherein the first plurality of pores are configured to enhance restructuring compared to the second plurality of pores.
地址 Bellevue WA US