发明名称 |
Bone cell delivery device |
摘要 |
Bone cages are disclosed including devices for biocompatible implantation. The structures of bone are useful for providing living cells and tissues as well as biologically active molecules to subjects. |
申请公布号 |
US9005944(B2) |
申请公布日期 |
2015.04.14 |
申请号 |
US200711906664 |
申请日期 |
2007.10.02 |
申请人 |
The Invention Science Fund I, LLC |
发明人 |
Harlow Ed;Jung Edward K. Y.;Langer Robert;Leuthardt Eric C.;Wood, Jr. Lowell L. |
分类号 |
C12N9/00;A61K9/48;A61K47/48;A61K9/00;A61L27/36;A61L27/38;C12N5/077;A61K35/12 |
主分类号 |
C12N9/00 |
代理机构 |
Dorsey & Whitney LLP |
代理人 |
Dorsey & Whitney LLP |
主权项 |
1. A method of making a device, comprising:
culturing bone cells in vitro on a scaffold to form an implantable structure; forming an internal cavity in the implantable structure; and selectively drilling, in the implantable structure, a first plurality of pores at a first location and a second plurality of pores at a second location, wherein the first location is discrete from the second location, wherein the first plurality of pores are configured to enhance restructuring compared to the second plurality of pores. |
地址 |
Bellevue WA US |