Bioabsorbable self-expanding endolumenal devices

摘要

Bioabsorbable self-expanding medical devices formed of an integral framework with a multiplicity of fenestrations are provided. The framework is continuous, non-filamentous, non-braided, and non-interlaced. The devices includes a non-blended hydrolysable co-polymeric material comprising an amorphous component with a glass transition temperature that is below ambient body temperature and a crystallizable component that possesses a crystalline melting point in excess of ambient body temperature. The devices radially expand from a compressed first diameter to an uncompressed second diameter equal to or greater than 1.5 times the first diameter within two minutes in an aqueous medium at 37° C. following release of a compressive force placed on the devices. Additionally, the medical device does not change axial length significantly as the radial dimensions of the devices are changed. Further, the medical devices may be constructed of different bioabsorbable polymers, polymer ratios, and/or different geometries and portions may bioabsorb at different rates.

主权项

1. A self-expanding support for a body conduit comprising:
a substantially tubular framework delimiting a multiplicity of fenestrations; a filter device attached to said tubular framework, said filter device comprising:
non-bioabsorbable frame elements; andbioabsorbable filter elements attached to said frame elements, wherein said bioabsorbable filter elements converge at a center region to form a generally conical structure with openings between said filter elements for fluid therethrough; wherein portions of said filter elements at said center region of said conical structure are bioabsorbed prior to portions of said filter elements located at a periphery of said filter elements, wherein said framework is continuous, non-filamentous, non-braided, and non-interlaced; wherein said framework is made of a non-blended hydrolysable co-polymeric material comprising an amorphous component with a glass transition temperature that is below ambient body temperature and a crystallizable component that possesses a crystalline melting point in excess of ambient body temperature; and wherein said framework expands radially from a compressed first diameter to an uncompressed second diameter below normal human body temperature without requisite for an externally applied force and without requisite for a thermal transition of said polymeric material.