摘要 |
<p>PROBLEM TO BE SOLVED: To provide a carbon dioxide foam-type external preparation for skin which has an enhanced absorption effect of carbon dioxide to skin and mucosa by finding out a percutaneous absorption enhancer which has an excellent percutaneous absorption-enhancing action of carbon dioxide to be combined with the carbon dioxide foam-type external preparation for skin in a solid, granular, fine grain, or powder form.SOLUTION: In a carbon dioxide foam-type external preparation for skin in a solid, granular, fine grain, or powder form containing acidic substances, carbon dioxide-generating substances which react with the acidic substances to generate carbon dioxide, and a percutaneous absorption enhancer of carbon dioxide, permeability of carbon dioxide to the skin can be enhanced by containing a liquid oil solution as the percutaneous absorption enhancer of carbon dioxide.</p> |