VACCINATING INFLUENZA VIRUS STRAIN B/60/WISCONSIN/2010/125

摘要

FIELD: medicine.SUBSTANCE: invention refers to medical virology and concerns a vaccinating influenza virus strain. The characterised strain B/60/Wisconsin/2010/125 is a reaccortant produced by crossing the epidemic virus B/Wisconsin/1/2010 with the cold-adapted heat-sensitive virus B/USSR/60/69 that is an attenuation donor. The strain B/60/Wisconsin/2010/125 is characterised by heat-sensitivity and cold-adaptation. The reassortant has inherited genes coding the surface antigens, haemagglutinine (HA) and neuraminidase (NA), from the epidemic virus and rest six genes coding internal non-glycosylated proteins, from the attenuation donor. The strain is deposited in the State Collection of Viruses of Federal State Budgetary Institution D. I. Ivanovskiy Research Institute of Virology, under No. 2723.EFFECT: invention can be used in practical health care for preventing the influenza rate in adults and children.1 dwg, 4 tbl