发明名称 METHOD FOR PRODUCING GLYCOLISED POLYPEPTIDE AGENT
摘要 FIELD: medicine.SUBSTANCE: method for producing an anti-inflammatory glycolised polypeptide agent with the use of commercial sea urchin (Strongylocentrotus droebachiensis) waste. A method involves extracting sea urchin inners in ethanol, separating the extract in a separator or a centrifuge, evaporating it, filtering the concentrate, performing gel chromatography, separating a fraction having molecular weight 5.5-7.0 kDa and drying it in the certain environment. The produced agent possesses the pronounced anti-inflammatory action.EFFECT: method enables improving purity of glycolised polypeptides.3 cl, 4 tbl, 1 dwg, 4 ex
申请公布号 RU2545703(C1) 申请公布日期 2015.04.10
申请号 RU20140114103 申请日期 2014.04.09
申请人 ZAKRYTOE AKTSIONERNOE OBSHCHESTVO "SANKT-PETERBURGSKIJ INSTITUT FARMATSII" 发明人 POZHARITSKAJA OL'GA NIKOLAEVNA;SHIKOV ALEKSANDR NIKOLAEVICH;MAKAROVA MARINA NIKOLAEVNA;MAKAROV VALERIJ GENNAD'EVICH;FOMICHEV JURIJ SERGEEVICH
分类号 A61K35/56;A61P29/00 主分类号 A61K35/56
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