发明名称 |
NOUVEAUX MEDICAMENTS COMPRENANT UNE COMPOSITION D'ANTICORPS ENRICHIE EN ISOFORME DE CHARGE MAJORITAIRE |
摘要 |
The present invention lies in the technical field of antibody therapies involving a mechanism of target-cell destruction by ADCC. It relates to purified antibody compositions, obtained by chromatographic fractionation of the various charge isoforms naturally present in an antibody composition and combining one or more chromatographic fractions corresponding to the predominant peak of the chromatogram, the resulting monoclonal antibody composition being enriched in said predominant peak, said peak representing at least 85% of the chromatogram of the composition obtained, for use as a medicament. |
申请公布号 |
FR3003171(B1) |
申请公布日期 |
2015.04.10 |
申请号 |
FR20130052360 |
申请日期 |
2013.03.15 |
申请人 |
LABORATOIRE FRANCAIS DU FRACTIONNEMENT ET DES BIOTECHNOLOGIES |
发明人 |
CHEVREUX GUILLAUME;BIHOREAU NICOLAS |
分类号 |
A61K39/395;C07K1/16;C07K16/08;C07K16/12;C07K16/28;C07K16/30;C07K16/34 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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