METHOD OF DETERMINING INTERNAL ENERGY OF BIOSPECIFICALLY INTERACTING SUSPENSION OF VOLUMETRIC AGGLUTINATION REACTION

摘要

FIELD: biotechnology.SUBSTANCE: invention can be used to determine the inner energy of biospecifically reacting suspension of volumetric agglutination reaction (VAR) with brucellosis or tularemia antibody solutions and suspensions of cells. For this purpose the measurement of temperature difference of test biospecifically reacting suspension of volumetric agglutination reaction and control biospecifically unresponsive suspension is carried out, in which the antibody solution or suspension of cell antigen is replaced by the heterologous ingredient.EFFECT: invention provides the ability of quantitative determination in SI system physical units of Joules and non-system calories of magnitude of the inner energy and work, respectively, shown and carried out as a result of the biospecific interaction of the active sires of antibodies and antigens in VAR suspension.1 tbl, 6 ex