| 摘要 |
FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to medicine, more specifically to an implanted device comprising a biologically compatible, biologically degradable polymer mixed with TMC278 (rilpivirine) and with one or more release-enhancing agents specified in a group consisting of poloxamers, polysorbates and a combination of dimethylsulphoxide (DMSO) and poly(vinylpyrrolidone) (PVP).EFFECT: device provides the extended release of the active ingredient for long periods of time.17 cl, 3 dwg, 5 tbl, 7 ex |
