发明名称 Use of PEDF-derived polypeptides for treating osteoarthritis
摘要 <p>Disclosed herein is a synthetic peptide, which has an amino acid sequence that has 20–39 amino acid residues. The synthetic peptide has at least 80% amino acid sequence identity to SEQ ID NO: 1, and includes at least 20 consecutive residues that has at least 90% amino acid sequence identity to residues 11–30 of SEQ ID NO: 1. Also disclosed herein are pharmaceutical compositions containing the synthetic peptide; and uses thereof. According to various embodiments of the present disclosure, the synthetic peptide is useful in treating osteoarthritis in a subject.</p>
申请公布号 AU2012390210(A1) 申请公布日期 2015.04.09
申请号 AU20120390210 申请日期 2012.09.20
申请人 MACKAY MEMORIAL HOSPITAL 发明人 TSAO, YEOU-PING;HO, TSUNG-CHUAN
分类号 C07K14/35;A61K38/17 主分类号 C07K14/35
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