Methods and Compositions for Managing Pain Comprising Dexmedetomidine Transdermal Compositions

摘要

Aspects of the invention include methods of managing pain in a subject by applying a transdermal delivery device containing a dexmedetomidine composition formulated to deliver a pain relieving effective amount of dexmedetomidine to a subject experiencing pain. In practicing methods according to certain embodiments, a transdermal delivery device having a dexmedetomidine composition is applied to a subject and is maintained in contact with the subject in a manner sufficient to deliver an amount of dexmedetomidine effective to manage pain in the subject. Also provided are transdermal delivery devices configured to deliver dexmedetomidine sufficient for practicing the subject methods, as well as kits containing the transdermal delivery devices.

主权项

1. A method of managing pain in a subject, the method comprising applying to a skin surface of a subject experiencing pain a transdermal delivery device comprising:
a dexmedetomidine composition, the dexmedetomidine composition comprising:
dexmedetomidine; anda pressure sensitive adhesive; and a backing layer, wherein the dexmedetomidine composition is formulated to deliver a an effective amount of dexmedetomidine to manage pain in the subject.