OPTIMIZE ANALYTE DYNAMIC RANGE IN GAS CHROMATOGRAPHY

摘要

A non-specific gas analyzer with a wide dynamic range of concentration is used to assess the gas sample for total load of volatile organic constituents, and then control either a dilution with neutral gas or the quantity of sample aspirated in order to consistently deliver an appropriate total load of volatile analyte to a high-sensitivity analyzer. Such high-sensitivity analyzers may be gas chromatography combined with mass spectrometry or related mass spectrometry configurations, such as selected ion flow tube mass spectrometry, gas chromatography combined with ion mobility spectrometry, or related ion mobility configurations such as differential mobility spectrometry.

主权项

1. A gas analyzer apparatus comprising:
a non-specific gas analyzer or sensor suitable for receiving a gas sample containing a volatile analyte to be measured; a high-sensitivity gas analyzer; and a mixing controller coupled to the non-specific gas analyzer or sensor and suitable for delivering an appropriate total load of volatile analyte to the high-sensitivity analyzer.