摘要 |
<p>Aspects of the disclosure relate to compositions and designs for synthetic material for implantation in a subject to promote tissue repair. In some embodiments, a synthetic mesh or patch is provided for promoting repair of a target tissue. In some embodiments, a synthetic mesh or patch is provided that comprises isotropically-distributed, non-woven electrospun fibers. In some embodiments, a mesh or patch is provided that has a central region that is thicker than one or more edges or comprises one or more perforations.</p> |