SIEVE VALVES, MICROFLUIDIC CIRCUITS, MICROFLUIDIC DEVICES, KITS, AND METHODS FOR ISOLATING AN ANALYTE

摘要

One aspect of the invention provides a sieve valve including: a substrate defining a channel; a flexible membrane adapted and configured for deployment at an intersection with the channel; and one or more protrusions extending into the channel from the substrate or the flexible membrane. The one or more protrusions define a plurality of recesses extending beyond the intersection between the channel and the flexible membrane.