发明名称 |
NEUTRALIZING ANTI-INFLUENZA A ANTIBODIES AND USES THEREOF |
摘要 |
The invention relates to antibodies and binding fragments thereof that are capable of binding to influenza A virus hemagglutinin and neutralizing at least one group 1 subtype and at least 1 group 2 subtype of influenza A virus. In one embodiment, an antibody or binding fragment according to the invention is capable of binding to and/or neutralizing one or more influenza A virus group 1 subtypes selected from H1, H2, H5, H6, H8, H9, H11, H12, H13, H16 and H17 and variants thereof and one or more influenza A virus group 2 subtype selected from H3, H4, H7, H1 0, H14 and H15 and variants thereof. |
申请公布号 |
CA2924559(A1) |
申请公布日期 |
2015.04.09 |
申请号 |
CA20142924559 |
申请日期 |
2014.10.01 |
申请人 |
HUMABS BIOMED SA;MEDIMMUNE, LLC |
发明人 |
BENJAMIN, EBONY;KALLEWAARD-LELAY, NICOLE;MCAULIFFE, JOSEPHINE MARY;PALMER-HILL, FRANCES;WACHTER, LESLIE L.;YUAN, ANDY;ZHU, QING;CORTI, DAVIDE;LANZAVECCHIA, ANTONIO;GUARINO, BARBARA;DEMARCO, ANNA |
分类号 |
C07K16/12;A61K39/42;A61P31/16;C07K16/46;C12N15/13;C12P21/08 |
主分类号 |
C07K16/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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