发明名称 TRUNCATED LYSOSOMAL ACID LIPASE
摘要 Recombinant human lysosomal acid lipase (rhLAL) containing an N-terminal truncation, a composition of truncated recombinant human LAL (TLAL), an isolated mixture comprising TLAL and at least one other form of rhLAL are disclosed. A method of purifying TLAL from a mixture of LAL proteins, pharmaceutical compositions comprising TLAL and methods of producing TLAL are further disclosed.
申请公布号 US2015098933(A1) 申请公布日期 2015.04.09
申请号 US201314377990 申请日期 2013.03.01
申请人 SYNAGEVA BIOPHARMA CORP. 发明人 Treece Erin Renae;Hsia Nelson;Xia Zhinan;Quinn Anthony
分类号 A61K38/46;C12N9/20 主分类号 A61K38/46
代理机构 代理人
主权项 1. A composition comprising an isolated recombinant truncated lysosomal acid lipase (TLAL).
地址 Lexington MA US